Huntington’s Disease, a cruel genetic curse that robs individuals of control over their own bodies, has long remained a therapeutic enigma. Recently, CUHK researchers may have unlocked a critical piece of the puzzle. By identifying PAPD5 as a key culprit in neuronal damage and showcasing the potential of the BCH001 inhibitor, they are opening a promising new chapter in the fight against this devastating condition.

Professional dancers move with intention through rehearsed and controlled movements but there is a deadly genetic disorder, Huntington’s Disease, which forces the body into an uncontrolled unlovely dance from unpredictable muscle movements. Scientist from CUHK has worked a wonder in discovering a novel molecule compound potentially effective in treating the disease, by uncovering the culprit for the neuronal DNA damage.